Break out

时间:2019-03-08 07:02:01166网络整理admin

A VIRAL protein that punches holes in bacteria could help scientists to devise new antibiotics. Bacteria infected with a virus called a filamentous phage live normally but occasionally belch out new copies of the phage. Now Denise Marciano and her colleagues at Rockefeller University in New York have found that a viral protein called pIV forms a pore in the bacterium’s cell membrane to let the phages out (Science, vol 284, p 1516). A mutant version of pIV makes cell membranes leaky by staying open too long, the researchers discovered. They suspect that harmful bacteria release toxins through similar channels. If so,